Expression of Preproendothelin-2 Splice Variant in Cat

Expression and characterization of a human carboxylesterase 2 splice variant.

CPT-11 [7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin or Irinotecan] is a carbamate prodrug that is activated in vivo by carboxylesterase (CES)-2 to SN-38 (7-ethyl-10-hydroxycamptothecin), a potent topoisomerase I inhibitor. There is high interindividual variation when CPT-11 is used in the treatment of colorectal cancer. Several splice variants of CES2 are reported in the ...

Comparison of Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variant 1 in Different Stages of Endometriosis

Splice Variant Search with Gene Expression Data

Alternative splicing is the phenomena that the pre-mRNA transcript from DNA is processed into different mRNAs by spliced different types of introns. The organism can acquire proteins as many times as genes. Therefore to find such splicing variants is risen in the post genome era. We investigate a new method to detect splicing variants with the gene expression data by the oligonucleotide array t...

A Novel Actin mRNA Splice Variant Regulates ACTG1 Expression

Cytoplasmic actins are abundant, ubiquitous proteins in nucleated cells. However, actin expression is regulated in a tissue- and development-specific manner. We identified a novel cytoplasmic-γ-actin (Actg1) transcript that includes a previously unidentified exon (3a). Inclusion of this exon introduces an in-frame termination codon. We hypothesized this alternatively-spliced transcript down-reg...

comparison of expression of growth hormone-releasing hormone and its receptor splice variant 1 in different stages of endometriosis

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